The Tsetogamus Creek occurrence lies in the Tsetogamus Creek drainage basin located about 17 kilometres northeast of Iskut village.

Locally, the highly dissected terrain of the Tanzilla Plateau is underlain by Intermontane Belt volcanic and sedimentary units of Upper Paleozoic to Lower Mesozoic age. Regional mapping by the Geological Survey of Canada (Open File 1080) indicates that the local geology comprises augite porphyritic meta-andesite belonging to the Lower Volcanic Unit of the Middle Triassic Tsaybahe Group.

In 1929, brief prospecting by W. George of Stewart identified chalcopyrite mineralization (assumed to be disseminated) and the area was subsequently staked with eight claims. The nature of the occurrence was not described.